ISOLATED RABBIT ATRIA WITH SYMPATHETIC NERVE SUPPLY
نویسندگان
چکیده
منابع مشابه
Effects of magnesium on isolated rabbit atria.
The cardiac effects of magnesium were studied on 40 spontaneously beating rabbit atria at 37 degrees C. Magnesium administered in doses of 30, 60, 120 and 240 mmol elicited dose dependent negative inotropic and chronotropic responses. Larger doses above 240 mmol caused complete atrial arrest. Further it was observed that propranolol with magnesium became more effective in blocking the positive ...
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The effect of angiotensin on the action of tyramine was studied in isolated rabbit left atria paced by point and field stimulation to more clearly define the interaction of angiotensin with the sympathetic nervous system. Administration of angiotensin resulted in similar increases in contractility in both point- and field-stimulated atria. In point-stimulated preparations only the muscle is sti...
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The effects of diphenylhydantoin (DPH), 1(H to 1 ( H M , were studied on the various types of cells in the isolated right atrial preparation and on the specialized cells of Bachmann's bundle in atrial preparations obtained from puppies. High concentrations of DPH ( 1 ( H M ) slowed sinoatrial rate but lower concentrations had little effect. These chronotropic effects of DPH were direct. DPH in ...
متن کاملActions of Diphenylhydantoin on the Electrical Properties of Isolated Rabbit and Canine Atria
The effects of diphenylhydantoin (DPH), 1(H to 1 ( H M , were studied on the various types of cells in the isolated right atrial preparation and on the specialized cells of Bachmann's bundle in atrial preparations obtained from puppies. High concentrations of DPH ( 1 ( H M ) slowed sinoatrial rate but lower concentrations had little effect. These chronotropic effects of DPH were direct. DPH in ...
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The effect of pretreatment with graded concentration of diltiazem on the inotropic responses to amrinone were studied on isolated atria of rabbit. The responses to amrinone were modified by diltiazem in a biphasic manner; initial potentiation followed by inhibition. The potentiation is proposed to be due to synergistic rise in cytosolic calcium ion concentration by diltiazem and amrinone. The i...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology and Chemotherapy
سال: 1959
ISSN: 0366-0826
DOI: 10.1111/j.1476-5381.1959.tb00260.x